Hyperemesis and H. Pylori

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Hyperemesis and H. Pylori

Postby jcroc » May 25, 2011 7:51 pm

Hi, I just wondered if anyone knows much about the possible relationship between hyperemesis and heliobacter pylori? I suffered severe HG during two pregnancies, one requiring TPN and both requiring long hospitalisations.

In the past year, I've had a few ongoing reflux problems and tested positive to heliobacter pylori - the reflux improved after treatment to remove the bacteria (and through ongoing use of somac), but my doctor thought it was worth doing an upper gastroscopy to rule out any serious damage. I did have some gastritis, but everything was otherwise normal. One thing he mentioned was he's experienced an association between HG and h. pylori infection. He knew of two women who had not had a recurrence of HG after having been treated for h. pylori.

I did a bit of a search on pubmed and noticed there does seem to be a significant, though by no means conclusive, association between the two. One study showed three women with non responsive HG treated for h. pylori, who had their symptoms resolve within two weeks.

This study showed h. pylori in 95 of 105 HG patients: http://www.asjog.org/journal/v2Issue2/3 ... %20393.pdf

Examples of rapid improvement on treatment: http://www.ncbi.nlm.nih.gov/pubmed/9890250

Systematic reviews (of several studies) finding links: http://www.ncbi.nlm.nih.gov/pubmed/12445985

A systematic review (again several studies) NOT finding a link:
http://www.ncbi.nlm.nih.gov/pubmed/18043570 (by questionnaire, which isn't the greatest method)

Seems like a good area to explore for research given the simplicity of h. pylori detection and treatement. You simply need to breathe into a bag after fasting, and the eradication treatment lasts two weeks.
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I am getting tested asap before pregnancy #3

Postby Stormlady » Sep 14, 2011 12:10 am


My husband was just reading about this in Ashli McCalls book, Beyond Morning Sickness. I hopped online and have been reading about if for over an hour. I am so hopeful! I think I may have h pylori. Must get tested. I really hope, if I do, that getting treated for it will solve my severe HG!!! Thank you for supplying all the links you did. I hope everyone on the forums becomes aware of this, to get tested!!!

God Bless You,
2X HG Survivor
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Postby MichellevsHG » Oct 24, 2011 2:12 pm

There is definitely a correlation between the severity of HG and h.plyori. I was test for h.p. at 10 months post-partum for continued nausea/vomiting. I tested negative for h.p. but I have severe GERD. I never had any issues with reflux until HG. :(
DD, 9/14/07, (6w -38w) Severe HG (induced due to PreE) - barely treated until 20w; 40+lbs weight loss; multiple ER/hospital visits, PICC, zofran, benedryl, zantac, & baby aspirin; new Ob at 21/22w; mild Polyhydramnios (37w)

Loss, 9/17/13 (11w6d), Aggressively treated severe HG from 5w - 5% weightloss in 6 days, IV protonix/fluids/zofran @ 8w; zofran pump, benedryl, phenergan, zantac, baby aspirin

Loss, 12/7/13 (4w5d)

Angel Sent to Heaven, 10/21/92 (7w4d), Undiagnosed/Untreated Severe HG
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Postby BetteHGSM » Oct 24, 2011 3:57 pm

I was tested extensively for H.Pylori....and several times....and do not have it....my mother in law who is a nurse, was convinced that I had it...so much so that she came to a doctors appointment and demanded I be tested for it....only to find out, they had....at that point...twice.
Mayah Elizabeth Teresa~ Halloween 2009~ SEVERE HG from 6 weeks to delivery at 36 weeks, medically necessary induction...PICC line and TPN veteran.
Mason Timothy Daniel~ 7/13/2012- SEVERE HG from 6 weeks to delivery at 39 weeks, medically necessary induction~mutiple midlines, IV hydration with home care from 12 weeks until delivery, aggressive medicinal treatment.
My HG Story with Mayah:
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Postby vcase » Dec 31, 2011 12:54 am

I tested postitve and was treated for hpylori prior to conciveing. I also had to have my galbladder removed. I had milder Hg the first time around which was imediatly following treatment for the h pylori. This time the HG is worse and I to have wandered if there is a coralation...

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Postby DebbieS » Dec 31, 2011 1:24 am

I tested positive for h.pylori and was treated during my 2nd pregnancy. Was tested before ttc for my 3rd preg & also during it, but was negative. It didn't seem to affect the severity for my situation.
DS 2003; Loss 2005.
DD 2007.
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Re: Hyperemesis and H. Pylori

Postby Mimilabeille » Mar 07, 2013 6:08 pm

Hello everybody,

I know this is a very old thread. Anyway, do not think ...there is a correlation between H. Pylori and HG. I do not have H. Pylori and I do have awful HG.:( But I do have an autoinmune disease called Hashimoto.

It may help.
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